Article
Atomic accuracy in predicting and designing noncanonical RNA structure.
Nature methods - 1 Apr 2010
Das Rhiju, Karanicolas John, Baker David
Abstract excerpt
We present fragment assembly of RNA with full-atom refinement (FARFAR), a Rosetta framework for predicting and designing noncanonical motifs that define RNA tertiary structure. In a test set of thirty-two 6-20-nucleotide motifs, FARFAR recapitulated 50% of the experimental structures at near-atom...
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