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Transcriptome profiling of embryonic retinal pigment epithelium reprogramming

2021-03-29

Abstract excerpt

The plasticity of human retinal pigment epithelium (RPE) has been observed during proliferative vitreoretinopathy, a defective repair process during which injured RPE gives rise to fibrosis. In contrast, following injury, the RPE of the embryonic chicken can be reprogrammed to regenerate neural retina in an FGF2-dependent manner. To characterize the mechanisms underlying embryonic RPE reprogramming, we used laser...

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Literature Corpus work
f7c82293-e640-58bf-9545-479ef5015f6a
DOI
10.1101/2021.03.28.437384
Open publication

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Transcriptome profiling of embryonic retinal pigment epithelium reprogrammingDOI 10.1101/2021.03.28.437384
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