Article

The luminal AAA+ ATPase torsinA mediates distinct mechanisms of nuclear-cytoplasmic communication by adopting different functional assembly states

2021-12-10

Abstract excerpt

<h4>ABSTRACT</h4> Chemical and mechanical nuclear-cytoplasmic communication across the nuclear envelope (NE) is largely mediated by the nuclear pore complex (NPC) and the linker of nucleoskeleton and cytoskeleton (LINC) complex, respectively. While NPC and LINC complex assembly are functionally related, the mechanisms responsible for this relationship remain poorly understood. Here, we investigated how the lumina...

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Literature Corpus work: f796caab-d445-53de-b399-469807e92c1b
DOI: 10.1101/2021.12.09.472013

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