Article

c-MYC-dependent transcriptional inhibition of autophagy is implicated in Cisplatin sensitivity in HPV-positive Head and Neck Cancer

2023-02-13

Abstract excerpt

<title>Abstract</title> <p>Autophagy is important for removal, degradation and recycling of damaged organelles, proteins, and lipids through the degradative action of lysosomes. In addition to its catabolic function, autophagy is important in cancer and viral-mediated tumorigenesis, including Human Papillomavirus (HPV) positive cancers. HPV infection is a major risk factor in a subset of Head and Neck Cancer (HNC...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f786ca33-e268-532f-9e1c-0f523b714fc0
DOI: 10.21203/rs.3.rs-2468300/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

c-MYC-dependent transcriptional inhibition of autophagy is implicated in Cisplatin sensitivity in HPV-positive Head and Neck CancerDOI 10.21203/rs.3.rs-2468300/v1Read

c-MYC-dependent transcriptional inhibition of autophagy is implicated in cisplatin sensitivity in HPV-positive head and neck cancerSemantic proximity Read

The Autophagy Process in Cervical Carcinogenesis: Role of Non-Coding-RNAs, Molecular Mechanisms, and Therapeutic TargetsSemantic proximity Read

Human Papilloma Virus and AutophagySemantic proximity Read

Human papillomavirus 16E6/E7 activates autophagy via Atg9B and LAMP1 in cervical cancer cellsSemantic proximity Read

HPV/E7 induces chemotherapy‐mediated tumor suppression by ceramide‐dependent mitophagySemantic proximity Read

Autophagy in Cervical Cancer: An Emerging Therapeutic TargetSemantic proximity Read

Autophagy regulates UBC9 levels during viral-mediated tumorigenesisSemantic proximity Read

Autophagy buffers Ras-induced genotoxic stress enabling malignant transformation in keratinocytes primed by human papillomavirusSemantic proximity Read

Expression of the human papillomavirus type 16 E7 oncoprotein induces an autophagy-related process and sensitizes normal human keratinocytes to cell death in response to growth factor deprivationSemantic proximity Read

CHK2-FOXK axis promotes transcriptional control of autophagy programs.Semantic proximity Read

HPV16 E5 deregulates the autophagic process in human keratinocytesSemantic proximity Read

Effects of Metformin on the virus/host cell crosstalk in human papillomavirus‐positive cancer cellsSemantic proximity Read