Article

Hospitalized premature infants are colonized by related bacterial strains with distinct proteomic profiles

2017-11-10

Abstract excerpt

During the first weeks of life, microbial colonization of the gut impacts human immune system maturation and other developmental processes. In premature infants, aberrant colonization has been implicated in the onset of necrotizing enterocolitis (NEC), a life-threatening intestinal disease. To study the premature infant gut colonization process, genome-resolved metagenomics was conducted on 343 fecal samples colle...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f7809e45-7c2f-507a-a0aa-94aa3dac1129
DOI: 10.1101/217950

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Hospitalized premature infants are colonized by related bacterial strains with distinct proteomic profilesDOI 10.1101/217950Read

Clinical sequelae of gut microbiome development and disruption in hospitalized preterm infantsSemantic proximity Read

The microbiome and metabolome of pre-term infant stool is personalized, and not driven by health outcomes including necrotizing enterocolitis and late-onset sepsisSemantic proximity Read

Development of the preterm infant gut and gastric residuals microbiomeSemantic proximity Read

Strain-level characterization of health-associated bacterial consortia that colonize the human gut during infancySemantic proximity Read

Unraveling the Microbiome of Necrotizing Enterocolitis: Insights in Novel Microbial and Metabolomic BiomarkersSemantic proximity Read

Metagenomic analysis of mother-infant gut microbiome reveals global distinct and shared microbial signaturesSemantic proximity Read

The Human Neonatal Gut Microbiome: A Brief ReviewSemantic proximity Read

Temporal bacterial and metabolic development of the preterm gut reveals specific signatures in health and diseaseSemantic proximity Read

Strain-resolved community genomic analysis of gut microbial colonization in a premature infant.Semantic proximity Read

Culture and molecular-based profiles show shifts in bacterial communities of the upper respiratory tract that occur with ageSemantic proximity Read

The Pulmonary Microbial Signatures of Early Stages of Severe Infection in ChildrenSemantic proximity Read

Gut microbiota genome features associated with brain injury in extremely premature infantsSemantic proximity Read