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Temporal bacterial and metabolic development of the preterm gut reveals specific signatures in health and disease

1 Dec 2016

Abstract excerpt

BACKGROUND: The preterm microbiome is crucial to gut health and may contribute to necrotising enterocolitis (NEC), which represents the most significant pathology affecting preterm infants. From a cohort of 318 infants, <32 weeks gestation, we selected 7 infants who developed NEC (defined rigorously) and 28 matched controls. We performed detailed temporal bacterial (n = 641) and metabolomic (n = 75) profiling of...

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PMID: 28034304
DOI: 10.1186/s40168-016-0216-8

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