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Article

Clinical sequelae of gut microbiome development and disruption in hospitalized preterm infants

27 Aug 2024

Abstract excerpt

Aberrant preterm infant gut microbiota assembly predisposes to early-life disorders and persistent health problems. Here, we characterize gut microbiome dynamics over the first 3 months of life in 236 preterm infants hospitalized in three neonatal intensive care units using shotgun metagenomics of 2,512 stools and metatranscriptomics of 1,381 stools. Strain tracking, taxonomic and functional profiling, and...

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PMID: 39197454
DOI: 10.1016/j.chom.2024.07.027

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