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Culture and molecular-based profiles show shifts in bacterial communities of the upper respiratory tract that occur with age

9 Jan 2015

Abstract excerpt

The upper respiratory tract (URT) is a crucial site for host defense, as it is home to bacterial communities that both modulate host immune defense and serve as a reservoir of potential pathogens. Young children are at high risk of respiratory illness, yet the composition of their URT microbiota is not well understood. Microbial profiling of the respiratory tract has traditionally focused on culturing common...

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PMID: 25575312
DOI: 10.1038/ismej.2014.250

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