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Article

Epigenetic and transgenerational mechanisms in infection-mediated neurodevelopmental disorders.

Translational psychiatry - 2 May 2017

Weber-Stadlbauer U

Abstract excerpt

Prenatal infection is an environmental risk factor for various brain disorders with neurodevelopmental components, including autism spectrum disorder and schizophrenia. Modeling this association in animals shows that maternal immune activation negatively affects fetal brain development and leads to the emergence of behavioral disturbances later in life. Recent discoveries in these preclinical models suggest that...

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Share to Autism Spectrum Disorder
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28463237
DOI: 10.1038/tp.2017.78
PMCID: PMC5534947

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