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Towards an armed oncolytic virus approach to glioblastoma treatment

2025-03-07

Abstract excerpt

Glioblastoma (GBM) is among the most aggressive and lethal human tumors. The current standard of care—surgical resection followed by chemotherapy—offers limited efficacy, as recurrence remains frequent and severe, underscoring the urgent need for novel therapeutic strategies. Photodynamic therapy (PDT) and oncolytic virotherapy have emerged as promising alternatives. PDT utilizes light-sensitive molecules to gener...

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Literature Corpus work
f760b9ce-b6cd-58e6-8f7e-8d9804f9d2a2
DOI
10.1101/2025.03.07.641877
Open publication

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