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Article

Genetic evidence from proteome-wide analysis identifies plasma proteins driving risk of respiratory tract infections.

Cytokine - 1 Apr 2026

Yuan Yuhua, Liu Bin, Chen Shuhui, Wang Manli, Zhao Shuyue, Mao Yingying

Abstract excerpt

BACKGROUND: Respiratory tract infections (RTIs) remain a major global cause of morbidity, yet the causal role of circulating plasma proteins in RTI susceptibility is unclear. We aimed to systematically identify plasma proteins that causally influence the risk of upper and lower respiratory tract infections (URTIs, LRTIs) using a proteome-wide Mendelian randomization (MR) framework. METHODS: We performed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 41678870
DOI: 10.1016/j.cyto.2026.157127

Genes

GFRA1
UBE2L6
APOE
CSF3
FKBP1B
FKBPL
IL1RL1
MST1
TNF
YAP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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