Article

Dissociating the effects of distraction and proactive interference on object memory through tests of novelty preference

2020-08-17

Abstract excerpt

Encoding information into memory is sensitive to distraction whilst retrieving that memory may be compromised by proactive interference from pre-existing memories. These two debilitating effects are common in neuropsychiatric conditions but modelling them preclinically to date is slow as it requires prolonged operant training. A step change would be the validation of functionally equivalent but fast, simple, high-...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f719aa70-27cc-51d6-b36d-385d325771eb
DOI: 10.1101/2020.08.16.253179

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Dissociating the effects of distraction and proactive interference on object memory through tests of novelty preferenceDOI 10.1101/2020.08.16.253179Read

High-THC <i>Cannabis</i> smoke impairs working memory capacity in spontaneous tests of novelty preference for objects and odors in ratsSemantic proximity Read

Spontaneous object exploration in a recessive gene knockout model of Parkinson’s disease: Development and progression of object recognition memory deficits in male <i>Pink1</i> -/- ratsSemantic proximity Read

Disturbances of novel object exploration and recognition in a chronic ketamine mouse model of schizophrenia.Semantic proximity Read

Optogenetic induction of the schizophrenia-related endophenotype of ventral hippocampal hyperactivity causes rodent correlates of positive and cognitive symptoms.Semantic proximity Read

Impaired visuospatial recognition memory but normal object novelty detection and relative familiarity judgments in adult mice expressing the APPswe Alzheimer's disease mutation.Semantic proximity Read

Object recognition test for studying cognitive impairments in animal models of Alzheimer s diseaseSemantic proximity Read

Differences in trait impulsivity do not bias the response to pharmacological drug challenge in the rat five-choice serial reaction time task.Semantic proximity Read

Conceptual, spatial, and cue learning in the Morris water maze in fast or slow kindling rats: attention deficit comorbidity.Semantic proximity Read

Differentiation of rodent behavioral phenotypes and methylphenidate action in sustained and flexible attention tasks.Semantic proximity Read

The effect of reduced dopamine D4 receptor expression in the 5-choice continuous performance task: Separating response inhibition from premature responding.Semantic proximity Read

Cognitive impairments in the STOP null mouse model of schizophrenia.Semantic proximity Read

Effects of D3-preferring agonist PD 128907 on compulsive behaviour and decision making as assessed by the 5C-CPTSemantic proximity Read