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Next Generation Sequencing of Amplified DNA of Circulating Tumor Cells in Resectable Non-Small Cell Lung Cancer: A Comparative Analysis with Primary Cancer Tissue and Cell-Free DNA

2024-04-25

Abstract excerpt

<title>Abstract</title> <p>Purpose Circulating tumor cells (CTCs) are thought to play a major role in the distant metastasis of lung cancer. However, their mutational profile has not been extensively studied. This study analyzed the amplified DNA from CTCs, using next generation sequencing to identify mutations and compare them with those found in primary cancer tissue and cell-free DNA (cfDNA). Methods Fifty p...

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Literature Corpus work: f7192692-1da5-5323-9754-f7baa1da53e2
DOI: 10.21203/rs.3.rs-4278611/v1

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