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Administration of Porphyromonas Gingivalis in Pregnant Mice Enhances Glycolysis and Histone Lactylation/ADAM17 Leading to Cleft Palate in Offspring

2023-11-23

Abstract excerpt

<title>Abstract</title> <p>Periodontal disease is a risk factor for many systemic diseases such as Alzheimer’s disease and adverse pregnancy outcomes. Cleft palate (CP), the most common congenital craniofacial defect, has a multifaceted etiology influenced by complex genetic and environmental risk factors such as maternal bacterial or virus infection. A prior case-control study revealed a surprisingly strong asso...

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Literature Corpus work
f70e64ff-484d-5e5f-bfd8-d90c904d80db
DOI
10.21203/rs.3.rs-3600828/v1
Open publication

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Administration of Porphyromonas Gingivalis in Pregnant Mice Enhances Glycolysis and Histone Lactylation/ADAM17 Leading to Cleft Palate in OffspringDOI 10.21203/rs.3.rs-3600828/v1
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