Article

CALR-Regulated Lactylation Modifications in Periodontitis: Insights from Bulk and Single-Cell RNA Sequencing

2026-02-22

Abstract excerpt

<title>Abstract</title> <p> Background Lactic acid accumulates in periodontal tissues during periodontitis, suggesting disrupted metabolism may contribute to disease progression. However, the role of lactic acid and its modifications, such as lactylation, remains unclear. Methods Gingival tissues were collected from healthy controls and periodontitis patients. Protein lactylation levels were evaluated through...

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Literature Corpus work: 4662eba1-66ae-5b5b-8961-ba2851491c86
DOI: 10.21203/rs.3.rs-7867472/v1

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