Neural crest mural cells of forebrain meninges harbor innate immune functions during early brain development and exhibit different responses to septic and toxic insults

Abstract excerpt

In vertebrates, the cephalic neural crest (CNC), an embryonic multipotent cell population, gives rise to meningeal derivatives, covering and protecting the developing forebrain. In postnatal life, the meninges exert a prime role in developing and maintaining the central nervous system’s homeostasis and help modulate the immune capacities of resident cells and the blood-brain barrier. However, their role in the emb...

Topics

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• Congenital gastrointestinal and neural anomalies
• Congenital heart defects research
• COVID-19 Impact on Reproduction
• Fetal and Pediatric Neurological Disorders
• Mosquito-borne diseases and control
• Prenatal Screening and Diagnostics
• Preterm Birth and Chorioamnionitis
• Reproductive System and Pregnancy

Identifiers and source

Literature Corpus work

f6e01c40-41e8-505b-9c7a-07f234ccf465

DOI

10.1101/2023.11.28.569020