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The role of phytochemicals in modulating breast cancer resistance protein at the blood-brain barrier and the blood-tumour barrier

2021-01-01

Abstract excerpt

The blood-brain barrier (BBB) and the blood-tumour barrier (BTB) represent insidious obstacles for the delivery of anti-cancer agents to solid brain tumours, not only because of their morphological features, but also due to the presence of the drug efflux transporter breast cancer resistant protein (BCRP), localised at both the BBB and BTB. This efflux transporter restricts the permeation of anti-cancer agents acr...

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Literature Corpus work
f6d5c3e3-9801-5dac-9bf2-5de6282eccfc
DOI
10.48780/publications.aston.ac.uk.00043163
Open publication

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