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Article

Modulation of drug-resistant membrane and apoptosis proteins of breast cancer stem cells by targeting berberine liposomes.

Biomaterials - 1 Jun 2013

Ma Xu, Zhou Jia, Zhang Cheng-Xiang, Li Xiu-Ying, Li Nan, Ju Rui-Jun, Shi Ji-Feng, Sun Meng-Ge, Zhao Wei-Yu, Mu Li-Min, Yan Yan, Lu Wan-Liang

Abstract excerpt

The recurrence of breast cancer is associated with drug-resistance of cancer stem cells (CSCs), while overexpression of cell membrane ATP-binding cassette (ABC) transporters and resistance of mitochondrial apoptosis-related proteins are responsible for the drug-resistance of CSCs. The targeting berberine liposomes were developed to modulate the resistant membrane and mitochondrial proteins of breast CSCs for the...

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Identifiers

PMID: 23518403
DOI: 10.1016/j.biomaterials.2013.02.066

Genes

ABCC1
ABCC2
ABCC3
ABCG2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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