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Mutant P53 modulation by cryptolepine through cell cycle arrest and apoptosis in triple negative breast cancer.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Oct 2024

Qayoom Hina, Mir Manzoor A

Abstract excerpt

BACKGROUND: Triple Negative Breast cancer is an aggressive breast cancer subtype. It has a more aggressive clinical course, an earlier age of onset, a larger propensity for metastasis, and worse clinical outcomes as evidenced by a higher risk of recurrence and a shorter survival rate. Currently, the primary options for TNBC treatment are surgery, radiation, and chemotherapy. These treatments however remain...

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PMID: 39216450
DOI: 10.1016/j.biopha.2024.117351

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