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Article

Molecular mechanism of myofibroblast formation and strategies for clinical drugs treatments in hypertrophic scars

14 Oct 2019

Abstract excerpt

Hypertrophic scars (HTS) commonly occurred after burn and trauma. It was characterized by the excessive deposition of extracellular matrix with the inadequate remodeling, which could result in severe physiological and psychological problems. However, the effective available prevention and treatment measures were still limited. The main pathological feature of HTS was the excessive formation of myofibroblasts, and...

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PMID: 31612497
DOI: 10.1002/jcp.29302

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