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Lipoaspirate-derived secretome activates NRF2 to restore redox homeostasis and attenuate pathological scar formation

2026-03-10

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> : Pathological scars are characterized by persistent fibroblast activation and excessive extracellular matrix (ECM) deposition. Although oxidative stress and dysregulated NRF2 signaling drive TGF-β1–mediated fibrosis in internal organs, their roles in cutaneous pathological scarring remain unclear. Adipose-derived stromal cell (ADSC) and lipoaspirate-derived e...

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Literature Corpus work
be320551-599a-5048-813b-d1f7d287faa5
DOI
10.21203/rs.3.rs-8578429/v1
Open publication

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Lipoaspirate-derived secretome activates NRF2 to restore redox homeostasis and attenuate pathological scar formationDOI 10.21203/rs.3.rs-8578429/v1
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