Article

Gut microbiome composition in Lynch syndrome with and without history of colorectal neoplasia and non-Lynch controls

2022-11-21

Abstract excerpt

<h4>Background: </h4> While Lynch syndrome (LS) is a highly penetrant colorectal cancer (CRC) syndrome, there is considerable variation in penetrance, few studies have investigated the association between microbiome and CRC risk in LS. We analyzed the microbiome composition among individuals with LS with and without personal history of colorectal neoplasia (CRN) and non-LS controls. Methods We sequenced the V4 re...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f6bb75b8-49d4-5807-ab8b-6aeb23462908
DOI: 10.21203/rs.3.rs-2260805/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Gut microbiome composition in Lynch syndrome with and without history of colorectal neoplasia and non-Lynch controlsDOI 10.21203/rs.3.rs-2260805/v1Read

Gut Microbiome Composition in Lynch Syndrome With and Without History of Colorectal Neoplasia and Non-Lynch ControlsSemantic proximity Read

An Evaluation of the Fecal Microbiome in Lynch Syndrome.Semantic proximity Read

Colorectal cancer in Lynch syndrome families: consequences of gene germline mutations and the gut microbiotaSemantic proximity Read

Gut microbial signatures are associated with Lynch syndrome (LS) and cancer history in Druze communities in Israel.Semantic proximity Read

Gut Microbiota Analysis in Postoperative Lynch Syndrome PatientsSemantic proximity Read

Loss of symbiotic and increase of virulent bacteria through microbial networks in Lynch syndrome colon carcinogenesisSemantic proximity Read

Gut microbiome signatures of colorectal cancer development are more pronounced in women compared to men in a population-based screening cohortSemantic proximity Read

Intratumoural pks Escherichia coli is associated with risk of metachronous colorectal cancer and adenoma development in people with Lynch syndromeSemantic proximity Read

Structure of the Mucosal and Stool Microbiome in Lynch SyndromeSemantic proximity Read

Using whole-genome sequencing (WGS) to plot colorectal cancer-related gut microbiota in a population with varied geographySemantic proximity Read

Metagenomic analysis of formalin-fixed paraffin-embedded tumor and normal mucosa reveals differences in the microbiome of colorectal cancer patientsSemantic proximity Read

Gut microbiota composition in colorectal cancer patients is genetically regulatedSemantic proximity Read