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Article

Gut Microbiota Analysis in Postoperative Lynch Syndrome Patients

30 Jul 2019

Abstract excerpt

Lynch Syndrome (LS) is a dominantly inherited condition with incomplete penetrance, characterized by high predisposition to colorectal cancer (CRC), endometrial and ovarian cancers, as well as to other tumors. LS is associated with constitutive DNA mismatch repair (MMR) gene defects, and carriers of the same pathogenic variants can show great phenotypic heterogeneity in terms of cancer spectrum. In the last...

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Identifiers

PMID: 31417532
DOI: 10.3389/fmicb.2019.01746

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