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Machine learning prediction models based on hub genes related to immune phenotypes in muscle-invasive bladder cancer treated with immune checkpoint blockade

2020-09-22

Abstract excerpt

<title>Abstract</title> <p>Background Bladder cancer is one of the most frequent cancer in the world. Muscle-invasive bladder cancer (MIBC) is a more aggressive subtype with higher morbidity and mortality. ICB therapy has shown potential for treating MIBC, but is limited due to the lack of predictive biomarkers. Methods 1601 MIBC transcriptomic profiles were obtained from 10 datasets. Unsupervised clustering of...

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Literature Corpus work
918fc580-83e8-534a-9d0e-d437703ede94
DOI
10.21203/rs.3.rs-75396/v1
Open publication

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Machine learning prediction models based on hub genes related to immune phenotypes in muscle-invasive bladder cancer treated with immune checkpoint blockadeDOI 10.21203/rs.3.rs-75396/v1
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