Article

Cisterna Chyli as an Evolutionary Incubator for Metastasis: Comparative Circulating Tumor Cell Phenotyping Across Cisterna Chyli, Peripheral Lymph and Blood in 614 Participants

2026-02-03

Abstract excerpt

<h4>Background: </h4> Circulating tumor cells (CTCs) are key intermediates of hematogenous metastasis, yet their phenotype is shaped by transit through distinct anatomical niches. The cisterna chyli is the central lymphatic conduit draining lipid-rich intestinal lymph and peripheral lymphatics into the venous system. We investigated whether the cisterna chyli functions as a phenotypic “incubator” for aggressive CT...

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Literature Corpus work: f685a417-8a8e-52fc-8e7a-fc5381ff3daa
DOI: 10.20944/preprints202602.0170.v1

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