Article

Interpreting new molecular genetics in myelodysplastic syndromes

2012-12-08

Abstract excerpt

Abstract The myelodysplastic syndromes (MDS) are a clinically and cytogenetically heterogeneous group of clonal diseases characterized by ineffective hematopoiesis, peripheral blood cytopenias, and an increased risk of progression to acute myeloid leukemia. The precise molecular mechanisms behind the development of MDS have remained elusive; however, the distinct sensitivity of this disease to DNA methyltransferas...

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Literature Corpus work: f684d8ea-f729-59d4-9aba-7a1f13c0436c
DOI: 10.1182/asheducation.v2012.1.56.3798194

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