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Article

Therapeutic regulation of cytoprotective pathways in the vascular endothelium

2011-01-01

Abstract excerpt

Vascular injury and endothelial dysfunction are recognised features of atherosclerosis, transplant vasculopathy, SLE and rheumatoid. Heme oxygenase-1 (HO-1) and complement inhibitory proteins (CIP) decay-accelerating factor (DAF) limit vascular injury. There is considerable interest in therapeutic manipulation of cytoprotective genes and statins induce HO-1 and DAF expression, while rapamycin (R) enhances HO-1 and...

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Literature Corpus work
f6690e56-e6b5-57df-a752-74d7175eb940
DOI
10.25560/6848
Open publication

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