Article

INTERCEPT pathogen reduction of platelet concentrates induces trans-arachidonic acids and affects eicosanoid formation

2022-04-07

Abstract excerpt

Gamma-irradiation of blood products is mandatory to avoid graft versus host disease in patients with immunosuppressed clinical conditions. Pathogen inactivation techniques were implemented to optimize safe blood component supply. The INTERCEPT treatment uses amotosalen together with UVA irradiation. The functional and molecular implications of these essential treatments have not yet been systematically assessed. T...

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Literature Corpus work: 4d37d2f4-17f7-5bd4-9b2d-ac4edd6dd3bf
DOI: 10.1101/2022.04.06.22273484

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