Article

Global landscape of the host response to SARS-CoV-2 variants reveals viral evolutionary trajectories

2022-10-21

Abstract excerpt

<h4>ABSTRACT</h4> A series of SARS-CoV-2 variants of concern (VOCs) have evolved in humans during the COVID-19 pandemic—Alpha, Beta, Gamma, Delta, and Omicron. Here, we used global proteomic and genomic analyses during infection to understand the molecular responses driving VOC evolution. We discovered VOC-specific differences in viral RNA and protein expression levels, including for N, Orf6, and Orf9b, and pinpo...

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Literature Corpus work: f665e5a6-e54e-56f1-b85f-d5a00161d1e4
DOI: 10.1101/2022.10.19.512927

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