Back to search

Article

Fragment tailoring strategy to design novel chemical entities as potential binders of novel corona virus main protease

2020-04-27

Abstract excerpt

The recent pandemic of novel corona virus (nCoV) infections (COVID19) has put the world on serious alert. The main protease of nCov (nCov-MP) cleaves the long polyprotein chains to release functional proteins required for replication of the virus and thus is a potential drug target to design new chemical entities in order to inhibit the viral replication in human cells. The current study employs state of art...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
f61547cb-6859-5874-8e92-beee5cd283a9
DOI
10.26434/chemrxiv.12129201.v2
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Fragment tailoring strategy to design novel chemical entities as potential binders of novel corona virus main proteaseDOI 10.26434/chemrxiv.12129201.v2
Select a neighboring publication to make it the new centre.