Article

Prenatal e-cigarette exposure induces region- and cell type-specific metabolic and developmental reprogramming

2026-06-24

Abstract excerpt

Prenatal e-cigarette exposure (PeCE) is increasingly prevalent and has been associated with adverse neurodevelopmental outcomes, yet how maternal vaping perturbs early brain development remains poorly understood. We integrated spatial transcriptomics, snRNA-seq and lipidomics to define neonatal rat brain responses to PeCE in rats at regional and cellular resolution. PeCE induced pronounced spatial heterogeneity in...

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Literature Corpus work: f5dc04e0-c1e6-5481-bdc3-b52d5c756cfc
DOI: 10.64898/2026.06.19.729385

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