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Article

Rescue of ethanol-induced FASD-like phenotypes via prenatal co-administration of choline.

Neuropharmacology - 15 May 2020

Bottom Riley T, Abbott Charles W, Huffman Kelly J

Abstract excerpt

Maternal consumption of alcohol during pregnancy can generate a multitude of deficits in the offspring. Fetal Alcohol Spectrum Disorders, or FASD, describe a palette of potentially life-long phenotypes that result from exposure to ethanol during human gestation. There is no cure for FASD and cognitive-behavioral therapies typically have low success rates, especially in severe cases. The neocortex, responsible for...

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PMID: 32044264
DOI: 10.1016/j.neuropharm.2020.107990

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