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Study on the mechanism that SNPs related to sex hormone metabolism regulate the imbalance of sex hormones and lead to BPH in rats

2025-12-12

Abstract excerpt

<title>Abstract</title> <p> <bold>Background:</bold> Benign prostatic hyperplasia (BPH) is a common disease in middle-aged and elderly men, and its etiology is not completely clear. the dihydrotestosterone (DHT) theory is the main mechanism to promote BPH. Our previous study to find the increase of estrogen and the decrease of androgen to estrogen ratio were high-risk factors for BPH. Because aromatase inhibito...

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Literature Corpus work
f5b6d7fe-1116-5f1a-b004-dd79fe891719
DOI
10.21203/rs.3.rs-7831971/v1
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Study on the mechanism that SNPs related to sex hormone metabolism regulate the imbalance of sex hormones and lead to BPH in ratsDOI 10.21203/rs.3.rs-7831971/v1
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