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Polygenic risk score predicting susceptibility and outcome of benign prostatic hyperplasia in the Han Chinese.

Human genomics - 22 May 2024

Hung Sheng-Chun, Chang Li-Wen, Hsiao Tzu-Hung, Lin Guan-Cheng, Wang Shian-Shiang, Li Jian-Ri, Chen I-Chieh

Abstract excerpt

BACKGROUND: Given the high prevalence of BPH among elderly men, pinpointing those at elevated risk can aid in early intervention and effective management. This study aimed to explore that polygenic risk score (PRS) is effective in predicting benign prostatic hyperplasia (BPH) incidence, prognosis and risk of operation in Han Chinese. METHODS: A retrospective cohort study included 12,474 male participants (6,237...

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Identifiers

PMID: 38778357
DOI: 10.1186/s40246-024-00619-3
PMCID: PMC11110300

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