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Naringenin Restores Osteogenic Differentiation in TNF-α-Treated Bone Marrow Mesenchymal Stem Cells by Targeting AKR1B1

2025-03-20

Abstract excerpt

<title>Abstract</title> <p>Background Chronic inflammatory microenvironments, driven by cytokines like TNF-α, disrupt bone remodeling by suppressing osteogenic differentiation, contributing to inflammatory bone diseases. While TNF-α inhibitors mitigate inflammation, they lack osteoprotective effects. Naringenin, a citrus flavonoid with antioxidative and anti-inflammatory properties, shows potential but its mecha...

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Literature Corpus work
f5717896-e55a-54eb-b512-331107e94c55
DOI
10.21203/rs.3.rs-6241423/v1
Open publication

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Naringenin Restores Osteogenic Differentiation in TNF-α-Treated Bone Marrow Mesenchymal Stem Cells by Targeting AKR1B1DOI 10.21203/rs.3.rs-6241423/v1
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