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A potent small molecule, AS2863619, enhances the osteogenic potential and ameliorates the inflammation-induced impairment of osteogenesis in periodontal ligament stem cells

2024-11-15

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> Periodontal ligament stem cells (PDLSCs) represent a promising source for the regeneration of periodontal tissues. However, these cells may experience functional alterations during in vitro expansion and culture, as well as under inflammatory conditions. In this study, we investigated AS2863619 (AS), a small molecule drug with potential applications in immune dis...

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Literature Corpus work
54248c73-f346-5afb-bf99-97a962175744
DOI
10.21203/rs.3.rs-5264326/v1
Open publication

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A potent small molecule, AS2863619, enhances the osteogenic potential and ameliorates the inflammation-induced impairment of osteogenesis in periodontal ligament stem cellsDOI 10.21203/rs.3.rs-5264326/v1
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