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Evaluation of 1<sup>st</sup>WHO Anti-Malaria Reference Reagent for Competition ELISA Harmonisation and Development of ADAMSEL Analytical Platform

2023-10-16

Abstract excerpt

This study focuses on harmonising the competition ELISA (cELISA) assay for Plasmodium falciparum ( P. falciparum ), using the 1 st WHO reference reagent for anti-malaria ( P. falciparum ) human reference serum (10/198). Antibody-mediated immune responses, against the Apical Membrane Antigen 1 (AMA1), play a significant role in protection against malaria. However, the sequence diversity of AMA1 and cross-reactivity...

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Literature Corpus work
f536274e-0d68-5a00-9484-66c2ef9c4345
DOI
10.1101/2023.10.16.23296996
Open publication

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