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Article

Reproducible quantification of cancer-associated proteins in body fluids using targeted proteomics.

Science translational medicine - 11 Jul 2012

Hüttenhain Ruth, Soste Martin, Selevsek Nathalie, Röst Hannes, Sethi Atul, Carapito Christine, Farrah Terry, Deutsch Eric W, Kusebauch Ulrike, Moritz Robert L, Niméus-Malmström Emma, Rinner Oliver, Aebersold Ruedi

Abstract excerpt

The rigorous testing of hypotheses on suitable sample cohorts is a major limitation in translational research. This is particularly the case for the validation of protein biomarkers; the lack of accurate, reproducible, and sensitive assays for most proteins has precluded the systematic assessment of hundreds of potential marker proteins described in the literature. Here, we describe a high-throughput method for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22786679
DOI: 10.1126/scitranslmed.3003989
PMCID: PMC3766734

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SRM

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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