Article

CYP168A1 from Pseudomonas aeruginosa may not be involved in the hydroxylation of medium chain-length fatty acids

2024-10-14

Abstract excerpt

Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen and the main cause of chronic lung infections in patients with cystic fibrosis (CF). Its resistance to multiple antibiotics poses a significant challenge in eradicating the bacteria from CF’s patients airways. Consequently, the World Health Organization (WHO) has classified it as priority health concern, underscoring the urgent need to identify new a...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f525d46c-f963-5fee-83ab-8308282dd644
DOI: 10.1099/acmi.0.000896.v2

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 8 closest

CYP168A1 from Pseudomonas aeruginosa may not be involved in the hydroxylation of medium chain-length fatty acidsDOI 10.1099/acmi.0.000896.v2Read

Selective hydroxylation of highly branched fatty acids and their derivatives by CYP102A1 from Bacillus megaterium.Semantic proximity Read

Substrate specificity of native and mutated cytochrome P450 (CYP102A3) from Bacillus subtilis.Semantic proximity Read

Elucidating the Pseudomonas aeruginosa fatty acid degradation pathway: identification of additional fatty acyl-CoA synthetase homologues.Semantic proximity Read

Hydroxylation of antitubercular drug candidate, SQ109, by mycobacterial cytochrome P450Semantic proximity Read

Oxidative biotransformation of fatty acids by cytochromes P450: predicted key structural elements orchestrating substrate specificity, regioselectivity and catalytic efficiency.Semantic proximity Read

Characterization of diverse natural variants of CYP102A1 found within a species of Bacillus megateriumSemantic proximity Read

Review: Antibiotic discovery in the age of structural biology - a comprehensive overview with special reference to development of drugs for the treatment of Pseudomonas aeruginosa infection.Semantic proximity Read

Cystic fibrosis.Semantic proximity Read