Article

Oxygen-glucose deprivation and reoxygenation on human cerebral organoids alters expression related to lipid metabolism

2020-04-01

Abstract excerpt

Ischemic stroke is one of the most common neurological disease. However, the impact of ischemic stroke on human cerebral tissue remains largely unknown; due to a lack of ischemic human brain samples. In this study, we used cerebral organoids derived from human induced pluripotent stem cells to evaluate the effect of oxygen-glucose deprivation/reoxygenation (OGD/R). We identified 15 differentially expressed genes (...

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Literature Corpus work: f4dec12f-4570-52a2-8ad8-12d70d1ae435
DOI: 10.1101/2020.03.31.017335

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