Article

Chronic lung diseases are associated with gene expression programs favoring SARS-CoV-2 entry and severity

2020-12-15

Abstract excerpt

<title>Abstract</title> <p>Patients with chronic lung disease (CLD) have an increased risk for severe coronavirus disease-19 (COVID-19) and poor outcomes. Here, we analyzed the transcriptomes of 605,904 single cells isolated from healthy and CLD lungs to identify molecular characteristics of lung cells that may account for worse COVID-19 outcomes in patients with chronic lung diseases. We observed a similar cellu...

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Literature Corpus work: f4bce20e-84e7-5ccf-8a07-cab80b8469ea
DOI: 10.21203/rs.3.rs-119865/v1

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