Article

Distinct Mucoinflammatory Phenotype and the Immunomodulatory Long Noncoding Transcripts Associated with SARS-CoV-2 Airway Infection

2021-05-18

Abstract excerpt

<h4>ABSTRACT</h4> Respiratory epithelial cells are the primary target for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We investigated the 3D human airway tissue model to evaluate innate epithelial cell responses to SARS-CoV-2 infection. A SARS-CoV-2 clinical isolate productively infected the 3D-airway model with a time-dependent increase in viral load (VL) and concurrent upregulation of airway im...

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Literature Corpus work: 84ad7f36-a97e-5507-806a-49901b80e388
DOI: 10.1101/2021.05.13.21257152

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