Article

The C-terminus of CFAP410 forms a tetrameric helical bundle that is essential for its localization to the basal body

2023-11-30

Abstract excerpt

Cilia are antenna-like organelles protruding from the surface of many cell types in the human body. Defects in ciliary structure or function often lead to diseases that are collectively called ciliopathies. Cilia and flagella associated protein 410 (CFAP410) localizes at the basal body of cilia/flagella and plays essential roles in ciliogenesis, neuronal development, and DNA damage repair. It remains unknown how i...

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Literature Corpus work: f486bd2c-4785-5a85-9773-7ccda18a91af
DOI: 10.1101/2023.11.30.569397

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