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Article

The C-terminus of CFAP410 forms a tetrameric helical bundle that is essential for its localization to the basal body.

Open biology - 1 Sept 2024

Stadler Alexander, De Liz Laryssa V, Gabriel Heloisa B, Alonso-Gil Santiago, Crickley Robbie, Korbula Katharina, Žagrović Bojan, Vaughan Sue, Sunter Jack D, Dong Gang

Abstract excerpt

Cilia are antenna-like organelles protruding from the surface of many cell types in the human body. Defects in ciliary structure or function often lead to diseases that are collectively called ciliopathies. Cilia and flagella-associated protein 410 (CFAP410) localizes at the basal body of cilia/flagella and plays essential roles in ciliogenesis, neuronal development and DNA damage repair. It remains unknown how...

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Source

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Identifiers

PMID: 39255848
DOI: 10.1098/rsob.240128
PMCID: PMC11500688

Genes

CFAP410

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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The C-terminus of CFAP410 forms a tetrameric helical bundle that is essential for its localization to the basal body.PMID 39255848Read ↗

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