Article

Upregulated FSP1 by GPD1/1L Mediated Lipid Droplet Accumulation Enhances Ferroptosis Resistance and Peritoneal Metastasis in Gastric Cancer

2024-10-11

Abstract excerpt

<title>Abstract</title> <p>To successfully metastasize, cancer cells must evade detachment induced cell death, known as anoikis. Unraveling the mechanisms that gastric cancer (GC) circumvent anoikis and achieve peritoneal metastasis especially during unanchored growth, could significantly improve patient outcomes. Our study reveals that GC cells exhibit increased lipid peroxidation, MDA production, and cell death...

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Literature Corpus work: f480e902-ab75-58db-a918-f107f0e6d0e2
DOI: 10.21203/rs.3.rs-4786302/v1

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