Article

The disruption of trace element homeostasis due to aneuploidy as a unifying theme in the etiology of cancer

2014-01-29

Abstract excerpt

<h4>Abstracts</h4> <h4>Abstract for Scientists</h4> While decades of cancer research have firmly established multiple “hallmarks of cancer” 1,2 , cancer’s genomic landscape remains to be fully understood. Particularly, the phenomenon of aneuploidy – gains and losses of large genomic regions, i.e. whole chromosomes or chromosome arms – and why most cancer cells are aneuploid remains enigmatic 3 . Another freque...

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Literature Corpus work: f473630b-a13a-522a-8057-ff78e2e52feb
DOI: 10.1101/002105

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