Article

PURIFICATION METHOD FOR ADENO-ASSOCIATED VIRAL VECTOR SEROTYPE 9 USING CERAMIC HYDROXYAPATITE CHROMATOGRAPHY AND ITS QUALIFICATION

2024-03-14

Abstract excerpt

<h4>ABSTRACT</h4> Adeno-associated virus (AAV) vectors can efficiently transduce exogenous genes into various tissues in vivo . Owing to their convenience, high efficiency, long-term stable gene expression, and minimal side effects, AAV vectors have become one of the gold standards for investigating gene functions in vivo , especially in non-clinical studies. However, challenges persist in efficiently preparing...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f4365272-96fc-5ce2-abb4-0118e3f9e2f6
DOI: 10.1101/2024.03.12.584728

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

PURIFICATION METHOD FOR ADENO-ASSOCIATED VIRAL VECTOR SEROTYPE 9 USING CERAMIC HYDROXYAPATITE CHROMATOGRAPHY AND ITS QUALIFICATIONDOI 10.1101/2024.03.12.584728Read

Efficient serotype-dependent release of functional vector into the culture medium during adeno-associated virus manufacturing.Semantic proximity Read

Manufacturing of recombinant adeno‐associated viruses using mammalian expression platformsSemantic proximity Read

A simplified purification protocol for recombinant adeno-associated virus vectorsSemantic proximity Read

Adeno‐Associated Virus Production, Purification, and TiteringSemantic proximity Read

Recent Advances in the Analysis Full/Empty Capsid Ratio and Genome Integrity of Adeno-associated Virus (AAV) Gene Delivery VectorsSemantic proximity Read

Unravelling the essential elements for recombinant adeno-associated virus (rAAV) production in animal cell-based platformsSemantic proximity Read

Standardized, Scalable, and Timely Flexible Adeno-Associated Virus Vector Production Using Frozen High-Density HEK-293 Cell Stocks and CELLdiscsSemantic proximity Read

Production, Processing, and Characterization of Synthetic AAV Gene Therapy VectorsSemantic proximity Read

Adeno-Associated Virus (AAV) as a Vector for Gene TherapySemantic proximity Read

Helper-free Production of Laboratory Grade AAV and Purification by Iodixanol Density Gradient CentrifugationSemantic proximity Read

Manufacturing of recombinant adeno-associated viral vectors for clinical trialsSemantic proximity Read

Organoids and microphysiological systems: Promising models for accelerating AAV gene therapy studiesSemantic proximity Read