Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A simplified purification protocol for recombinant adeno-associated virus vectors

1 Jan 2014

Abstract excerpt

We describe a new rapid, low cost, and scalable method for purification of various recombinant adeno-associated viruses (rAAVs) from the lysates of producer cells of either mammalian or insect origin. The method takes advantage of two general biochemical properties of all characterized AAV serotypes: (i) low isoelectric point of a capsid and (ii) relative biological stability of the viral particle in the acidic...

Source

Identifiers

PMID: 26015974
DOI: 10.1038/mtm.2014.34

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A simplified purification protocol for recombinant adeno-associated virus vectorsPMID 26015974Read ↗

Manufacturing of recombinant adeno‐associated viruses using mammalian expression platformsSemantic proximity Read ↗

Manufacturing of recombinant adeno-associated viral vectors for clinical trialsSemantic proximity Read ↗

Production and Discovery of Novel Recombinant Adeno‐Associated Viral VectorsSemantic proximity Read ↗

Efficient serotype-dependent release of functional vector into the culture medium during adeno-associated virus manufacturing.Semantic proximity Read ↗

Production of Recombinant Adeno-Associated Virus VectorsSemantic proximity Read ↗

Production and purification of serotype 1, 2, and 5 recombinant adeno-associated viral vectorsSemantic proximity Read ↗

Rapid, Simple, and Versatile Manufacturing of Recombinant Adeno-Associated Viral Vectors at ScaleSemantic proximity Read ↗

Unravelling the essential elements for recombinant adeno-associated virus (rAAV) production in animal cell-based platformsSemantic proximity Read ↗

Molecular design for recombinant adeno-associated virus (rAAV) vector productionSemantic proximity Read ↗

Production and Titering of Recombinant Adeno-associated Viral VectorsSemantic proximity Read ↗

PURIFICATION METHOD FOR ADENO-ASSOCIATED VIRAL VECTOR SEROTYPE 9 USING CERAMIC HYDROXYAPATITE CHROMATOGRAPHY AND ITS QUALIFICATIONSemantic proximity Read ↗

A Simplified Baculovirus-AAV Expression Vector System Coupled With One-step Affinity Purification Yields High-titer rAAV Stocks From Insect CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.