Article

Megakaryocyte and erythroblast DNA in plasma and platelets

2022-10-04

Abstract excerpt

<h4>ABSTRACT</h4> Circulating cell-free DNA (cfDNA) fragments are a biological analyte with extensive utility in diagnostic medicine. Understanding the source of cfDNA and mechanisms of release is crucial for designing and interpreting cfDNA-based liquid biopsy assays. Using cell type-specific methylation markers as well as genome-wide methylation analysis, we determined that megakaryocytes, the precursors of anu...

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Literature Corpus work: f42fd8c1-7582-53af-9bc1-cf601f716e23
DOI: 10.1101/2022.10.03.510502

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