Article

Alternate subunit assembly diversifies the function of a bacterial toxin

2019-04-30

Abstract excerpt

Bacterial toxins with an AB 5 architecture are central to bacterial pathogenesis. Functionally diverse and evolutionarily distant AB 5 toxins adopt synonymous structures in which a discrete domain of the toxin’s active (A) subunit is inserted into a ring-like platform comprised of five delivery (B) subunits. Salmonella Typhi, the cause of typhoid fever, produces an unusual A 2 B 5 toxin known as typhoid toxin...

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Literature Corpus work: f406e171-4669-5d6a-b488-4c84bd0fd420
DOI: 10.1101/624130

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